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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7510 | Leucylarginylproline | RAAS | |
Leucylarginylproline is an inhibitor of angiotensin-converting enzyme (ACE) (IC50 : 0.27μM). | |||
T7686 | Ramiprilat | RAAS | |
Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. | |||
T1605 | Enalapril | MK-421 | RAAS , MRP |
Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. | |||
T1484 | Perindoprilat | Perindoprilate | RAAS , MRP , AChR |
Perindoprilat (Perindoprilate) is an angiotensin-converting enzyme inhibitor. | |||
T1145 | Diminazene Aceturate | Others , Serine Protease , Parasite | |
Diminazene is a trypanocidal agent. | |||
T13865 | Resorcinolnaphthalein | RAAS | |
Resorcinolnaphthalein is a specific enhancer of angiotensin-converting enzyme 2 (ACE2) (EC50 value of 19.5 μM). | |||
T1489 | Fosinopril sodium | SQ28555 | RAAS |
Fosinopril sodium is a phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug that is converted to its active metabolite fosinoprilat. | |||
T16116 | MLN-4760 | RAAS | |
MLN-4760 is an angiotensin-converting (ACE2) inhibitor(human ACE2;IC50=0.44 nM). It also has excellent selectivity (>5000-fold) versus related enzymes including human testicular ACE (IC50, >100 μM) and bovine carboxypept... | |||
T8270 | Deserpidine | Harmonyl | RAAS |
Deserpidine (Harmonyl) is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive propertie... | |||
T5S0106 | Peimisine | Ebeiensine | RAAS , AChR |
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe... | |||
TP1828 | N-Acetyl-Ser-Asp-Lys-Pro | RAAS | |
Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethalit... | |||
T13299 | Vicenin 3 | RAAS | |
Vicenin 3 is an inhibitor of angiotensin-converting enzyme (ACE; IC50: 46.91 μM) from the aerial parts of Desmodium styracifolium. | |||
T5796 | Plantainoside D | Isoplantamajoside | RAAS , PKC |
Plantainoside D (Isoplantamajoside) shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibitory activity in vitro with the IC(50) value of 2.17 mM, it ... | |||
T3281 | Delapril hydrochloride | indalapril,Alindapril Hydrochloride,Delapril Hydrochloride,CV 3317 | RAAS |
Delapril hydrochloride (indalapril) is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites bind completely to and inhibit angiotensin-converting enzyme... | |||
T21418 | Lisinopril | Linopril,Zestril,Prinivil,Lisipril | RAAS |
Lisinopril (Prinivil), the angiotensin-converting enzyme (ACE) inhibitor, is used primarily in the treatment of high heart failure, blood pressure, and heart attacks. It is also used for preventing eye and kidney complic... | |||
T3851 | Vicenin 2 | Vicenin -2 | RAAS |
Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-glucosidase, PTP1B, and RLAR. Vicenin 2 has hepatoprotective,... | |||
T7808 | Alacepril | Cetapril,DU-1219 | RAAS |
Alacepril (DU-1219) is a relatively novel angiotensin-converting enzyme inhibitor, used as an antihypertensive | |||
T2486 | IOWH-032 | IOWH032,IOWH 032 | CFTR , Autophagy |
IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea. | |||
T3753 | Sinapinic Acid | Sinapic acid,Synapoic acid | Apoptosis , RAAS , Reactive Oxygen Species , HDAC |
Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinap... | |||
T5030 | Zofenopril calcium | SQ26991,Zofenopril (calcium) | RAAS , Reactive Oxygen Species |
Zofenopril calcium (SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metabolic hydrolysis yielding the active free sulfhydryl compound z... |